Data-driven approaches to understand patterns in human diseases
Data-driven approaches to understand patterns in human diseasesData-driven approaches to understand patterns in human diseasesData-driven approaches to understand patterns in human diseases
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QUESTIONS OF INTEREST TO US
What are shared genetic pathways (using rare/common/structural variants) associated with complex human diseases?
What are the mechanisms via which risk factors associate with disease of interest?
Are there causal pathways among these interrelationships?
How do gene-gene and gene-environment interactions affect these interrelationships?
How can we effectively visualize these big data networks?
How do sex and ancestry impact development of disease mechanisms that can guide improved clinical interventions in underrepresented groups in medicine?
How do we leverage these new discoveries to improve prediction accuracy of risk of complex diseases?
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